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CimaterolComplete info about CimaterolCimaterol is a stimulant, a fat burner, and similar to clenbuterol in many ways—and different in some very important ones. Both Clen and cimaterol are beta-adrenergic agonists, and thus are both anabolic as well as thermogenic (1)(5). Also, both stimulate your adrenal glands, increase your body temperature, raise your heart rate, etc., i.e. they mimic the "Fight or Flight" response quite well. Cimaterol, however, may stimulate the beta-1, 2, and 3 receptors while Clen only stimulates the beta 2 and 3 receptors. This may cause increased fat burning by cimaterol when compared with clenbuterol. Also, a far greater portion of brown adipose tissue is burned with the use of Cim over Clen, as far as I can tell. Cimaterol stimulates both lypolisis (burning fat, the release of free fatty acids and glycerol) as well as inhibit lypogenesis (gaining fat, the incorporation of 14C into fatty acids from [14C] glucose) and may even do both more effectively than Clen, possibly making it a more potent fat burner. In addition, it stimulates protein synthesis and thus could increase fat free mass via this mechanism (1) while at the same time burning fat. After a couple of weeks, however, the anabolic effects might lessen, as one study showed that weight gain (with fat loss, ergo a PURE muscle gain concurrent with fat loss) halted after 14 days (3). Energy metabolism has been shown to be greatly increased as well (4). Cimaterol also stimulates blood flow and causes acute mobilization of nitrogen (alanine), significantly increases amino acid uptake in muscles, and mobilizes lactic acid out of muscles (2). Thus, it may not have the athletic performance (endurance and possibly speed) decreasing effects of Clen . This is pure speculation on my part, and Cim may still have some of the performance decreasing effects of Clen, but as other beta-andrenergic-agonists like ephedrine don't, there is no reason to think Cim does. In any case, a lot of the studies seem to indicate that cimaterol is actually more potent for fat burning than Clen is. "Until some new synthetic beta-3 agonist is commercially available, the beta agonist of choice is still clenbuterol (although the STRONGER cimaterol is available as a research chemical in the U.S.)." "Though it's yet to be tested in humans, animal studies have determined that Cimaterol is a more powerful beta-agonist than clenbuterol, promotes protein retention and accretion, and has shown powerful anti-catabolic properties in cases of cancer or burns." So not only is this stuff a great fat-burner, it's anti-catabolic. Unfortunately, it downregulates the beta receptors just as Clen does (3), so a 3 week on/1 week off type of schedule may be appropriate, as would the addition of ketotifen after every 3 weeks (and not going off the cimaterol; so in 4 weeks on cimaterol, every 4th week you'd be adding in 2-3 mgs of ketotifen every night before you go to bed). You could also use 50mgs of benadryl instead of the ketotifen, in the same manner. As with any new drug, caution should be taken with this stuff. A dose of 0.15 milligram/kilogram administered subcutaneously is the standard dose in a lot of human studies. That's a fraction of any sort of dangerous dose, as you can see. References
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